Melatonin, Nature’s Healer for the Nation

 

 

 

Melatonin is a hormone found within the body.  Its greatest influence is over the body’s sleep cycle. It has however, another surprising ability.  Melatonin is a powerful anti-oxidant.  An anti-oxidant is a substance that binds to ‘free radicals’ in the human body.  Free radicals are toxins that roam the body.  They are highly reactive molecular chains that seek out other molecules to bind with.  This binding can result in a harmful or even carcinogenic substance that can play havoc with the body’s systems. 

 

Anti-oxidants are like the body’s police force, patrolling the blood, cells, tissues and organs of the brain.  When they happen upon a free radical, they bond with it, tying its molecular arms so that it cannot cause any damage by binding with other locations.

 

Toxic chemicals like fluoride, along with unbound protein strands like Glutamate and aspartate, are free radicals.  They are highly reactive substances that in large numbers can bind to chemicals, cells, and even neurons in the body to produce devastating effects.  By injecting Monosodium Glutamate directly into the brain of a creature, scientists can cause massive destruction of the brain cells that this free radical comes in contact with.  But when large amounts of Melatonin are present in the region that the MSG targets, the MSG fails to destroy the brain cells.  Researchers have described the ability of Melatonin to stop the damage that MSG causes as a neuroprotective effect.[1] 

 

The protective effects of Melatonin do not end with the brain.  Since its discovery as a free radical scavenger in 1993, over 800 publications have confirmed Melatonin’s ability to neutralize harmful molecules in the body.[2] 

 

The pineal gland produces Melatonin naturally within the body.  The chief role of Melatonin seems to be the creation of the natural sleep cycle of people and animals.  During the day, people’s Melatonin levels drop considerably, while in the evening this hormone becomes more prevalent in the blood.  Melatonin counteracts dopamine, which is the hormone most utilized during the daytime hours.  People with good sleep cycles show a balance between these two chemicals.  However, the pineal gland loses its ability to create Melatonin as the body ages.  This reduction in Melatonin levels can be linked to all manner of physical ailments.  Luckily, synthetic Melatonin is easily available, and in studies has shown remarkable properties that improve all manner of physical conditions from insomnia to cancer. 

 

 

 

 

Sleep Disorders

 

Since Melatonin is the natural hormone that induces sleep, ingesting a small dosage in tablet form is an effective cure for insomnia.  Unlike prescription sleeping pills, it is not addictive, and allows a person to wake with no residual effects of drowsiness.  Its use as a sleep aid has been documented in many areas of research.  Melatonin has been used to help blind children establish a normal sleep pattern.[3] It has been used to successfully treat chronic insomnia in children.[4]  It has even been used as an alternative to general anesthetic in children afraid to take an MRI.[5]  Melatonin has been found to “be a safe, inexpensive, and a very effective treatment of sleep-wake cycle disorders,” with no side effects or development of resistance to it.[6] 

 

Pfizer, one of the worlds largest drug companies, offers Unisom SleepGels to help adults and children over 12 to fall asleep. 

 

‘www.rxlist.com’ lists Unisom’s side effects as:

 

General: Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of mouth, nose, and throat.

Cardiovascular System: Hypotension, headache, palpitations, tachycardia, extrasystoles.

Hematologic System: Hemolytic anemia, thrombocytopenia, agranulocytosis.

Nervous System: Sedation, sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesia, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, neuritis, convulsions.

GI System: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation.

GU System: Urinary frequency, difficult urination, urinary retention, early menses.

Respiratory System: Thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness.

Sometimes the side effects of a drug sound worse than the condition they are meant to prevent.

 

If Melatonin is such a successful sleep aid that is not addictive, has no side effects, and is gentle enough to use on children under of all ages, why aren’t physicians prescribing it to the general public?  Why instead do they prescribe drugs with long lists of side effects?

 

Money.

 

Have you ever been at a physician’s office when a pharmaceutical sales person comes by?  Have you seen all the free samples and little note pads that the doctors use?  Those freebies come from drug companies.  The drug companies are major funders of medical research.  They even make large sums of money available to medical students to assist with their education. 

 

What business do drug sales representatives have in a doctor’s office? 

 

They are there to sell their drug.  They influence the choice of prescriptions that doctors make.  How often have you gone into a doctor’s office and come out with a suggestion instead of a prescription?  Did the doctor ever tell you just to put some ice on it, a simple ointment, a bandage, or say that it will just get better on its own?  Doctors give out prescriptions for many items that you can’t get on the open shelf of a drug store.  In many cases, the prescription is for a specific name of drug that only one company makes. 

 

By practicing the prescription doctrine, physicians do their part to line the pockets of the pharmaceutical companies that help fund their profession. 

 

The main reason that pharmaceutical companies fund research is to find a pill that can treat an ailment and that that pill can be patented to guarantee their exclusive right to profit from the drug.

 

The reason that physicians do not prescribe Melatonin to their sleep deprived patients is this:

 

No pharmaceutical company can make exclusive profit from it.

 

Melatonin is a naturally occurring hormone that cannot be patented by any company.  It is inexpensive to produce.  A four-month supply may cost you about ten dollars.  At that price, how can a pharmaceutical company generate the kind of profit they are used to?

 

Sleep disorders are not the only thing that you won’t see Melatonin prescribed for.  Medical research has discovered over a dozen other ailments that can be treated by an inexpensive dose of Melatonin.  From ulcers to bladder problems, epilepsy to cancer, reports published in scientific journals sing the praises of Melatonin, while the physicians across the country are silent.

 

Instead of healthy natural cures we are inundated with high priced drugs that have side effect lists that read like an encyclopedia.

 

The following sections outline the scientifically proven facts about Melatonin.  These are the ailments that a simple, inexpensive cure may rectify.  For those of you who are ready to take a stand against the profiteering of drug companies that bloat themselves at the price of our health, take this knowledge to your doctor and ask what single prescription medication can offer all these benefits without side effects and a thousand dollar-a-day price tag.

 

 

 

Gastrointestinal Disorders

 

Melatonin is a hormone that is essential to gastrointestinal health.  It is found in this system at 10 to 100 times the concentration found in the blood.  It has an important protective effect, and has been suggested in the treatment and prevention of gastric ulcers,[7] as well as “colorectal cancer, ulcerative colitis, gastric ulcers, irritable bowel syndrome, and childhood colic.”[8]  Perhaps there is a link between the increase in Crohn’s and Colitis disease and the prevalence of MSG in the diet.  Melatonin may be one form of treatment that could help those afflicted with these disorders. 

 

More research in this direction is definitely needed.

 

Infant Toxicity

Septic shock is a very serious condition that some infants are born with.  The baby is born with such a large amount of toxic elements in its system that little hope is offered to the parents.  Many newborns with this condition die within a few days of delivery.  Doctors at the University of Texas Health Science Center, San Antonio, gave ten septic babies large doses of Melatonin within 12 hours of birth.  These babies had a survival rate of 100%, while the septic babies that did not receive Melatonin suffered a 30% mortality rate before they were four days old.[9]

 

Our hearts go out to the parents of these infants.  Hopefully, this groundbreaking research will protect many more newborns to come.

 

Attention Deficit Hyperactive Disorder

At seven years old, little Johnny was found to be more hyper than the other children.  His mother could not get him to keep still.  A veritable ball of energy, he was always bouncing from here to there, never able to keep focused on a task.  The year was 1974, long before the invention of Ritalin.  ADHD was not even a recognized condition then.  Little Johnny’s hyperactivity was not even formally diagnosed.  His mother was desperate, and the doctor was only too willing to prescribe Phenobarbital, a serious anti-psychotic and highly addictive substance, to counteract his erratic behavior. 

 

If only Johnny’s mother had known what research shows now.

 

MSG intake during pregnancy may well have caused the condition that little Johnny suffered from.  MSG in the adolescent diet could further aggravate the child’s hyperactivity.  ADHD is linked to a problem in the dopamine levels within the body.[10]  Increased dopamine levels in the body are linked to the hyper active behaviors that ADHD children suffer.  Currently Ritalin is the most commonly prescribed medication for reducing the actions of dopamine, but there is a better alternative.  Dopamine can be naturally controlled by the introduction of increased Melatonin.[11] 

 

By removing MSG and all food ingredients that contain Glutamate from the diet, and giving Melatonin time-release capsules to these ADHD children, a natural balance could occur between the two hormones, creating an equalibrium in the child.  This could reduce both the level of hyperactivity and the difficulty with attention span that these children have.

 

How do I know that Melatonin and reduction in dietary Glutamate could cure ADHD?

 

I was little Johnny.  For thirty-five years my family has suffered from my hyperactive state.

 

A year ago I started taking Melatonin on a daily basis.  By removing all sources of free-Glutamate from my diet, and leveling out my dopamine levels with melatonin, I have been able to completely reduce all symptoms of ADHD that I had.  I now know the pleasure of sitting still, and the bliss of uninterrupted concentration.

 

We have two sons that are also ADHD possibly because of MSG.  By giving them Melatonin and reducing their glutamate intake we are protecting them not only from further poisoning, but also from the following side effects of the Ritalin that doctors have been pushing on ADHD children: 

·    drug addiction

·    nervousness and insomnia

·    nausea and vomiting

·    dizziness

·    headaches

·    changes in heart rate and blood pressure (usually elevation of both, but occasionally depression)

·    skin rashes and itching

·    abdominal pain

·    weight loss

·    digestive problems

·    toxic psychosis

·    psychotic episodes

·    severe depression upon withdrawal

·    loss of appetite (may cause serious malnutrition)

·    tremors and muscle twitching

·    fevers, convulsions, and headaches (may be severe)

·    irregular heartbeat and respiration (may be profound and life threatening)

·    anxiety, restlessness

·    paranoia, hallucinations, and delusions

·    excessive repetition of movements and meaningless tasks

·    while death due to non-medical use of Ritalin is not common, it has been known to occur.

Narconon: www.drug-sideeffects.com/ritalin.htm

 

Very little is known about the way Ritalin (known as methylphenidate) affects ADHD symptoms. “There is neither specific evidence which clearly establishes the mechanism whereby methylphenidate produces its mental and behavioral effects in children, nor conclusive evidence regarding how these effects relate to the condition of the central nervous system.”[12]

 

Not very reassuring words for a drug that doctors are passing out to children in record numbers. 

 

The number of children diagnosed with this disorder grows each year, and every year the number of Ritalin prescriptions increase.  While the bank accounts of the pharmaceutical giant Novartis (Ritalin’s creator) are expanding, the pocket books of parents dealing with the disorder are shrinking.  Ritalin prescriptions can be a life sentence.  Children with ADHD carry it with them into adulthood.

 

The American Drug Enforcement Agency has targeted Ritalin as a drug that is widely abused. 

 

“the primary legitimate medical use of methylphenidate (Ritalin®, Methylin®, Concerta®) is to treat attention deficit hyperactivity disorder (ADHD) in children. The increased use of this substance for the treatment of ADHD has paralleled an increase in its abuse among adolescents and young adults who crush these tablets and snort the powder to get high. Youngsters have little difficulty obtaining methylphenidate from classmates or friends who have been prescribed it. Greater efforts to safeguard this medication at home and school are needed.”

                                                                                                              http://www.dea.gov/concern/methylphenidate.html

 

Ritalin could make the lives of ADHD children more difficult than they already are.

 

Melatonin, on the other hand, has documentation supporting its natural suppression of dopamine.[13]  Unlike Ritalin, Melatonin is not addictive, cannot be used to get high, costs pennies to use, is found naturally in the body, and has none of the dangerous side effects that Ritalin has.

 

Melatonin has helped my two sons and myself to overcome the ADD and ADHD that has affected us.  Melatonin supplements, along with the removal of glutamates from our diet, have created a dramatic change for the better.

 

It is a shame that physicians have not directed parents to a more natural and affordable way of treating ADHD.  One that not only may prove more effective then Ritalin, but with far less side effects for the child as well.

 

 

Autism

 

Previous paragraphs in this book outlined the similarities between ADHD and autism.  Research now suggests that the Melatonin that could help ADHD sufferers may also help those with autism as well.  Individuals with autism have considerably lower levels of Melatonin in their bodies than healthy subjects.[14]   This may cause many imbalances within the body’s systems.  Perhaps Melatonin could be used to counteract some of the behaviors that are currently controlled by dangerous anti-psychotic drugs.

 

Currently there are no drugs specific to the treatment of autism.  As a case manager for autistic individuals, I have sat in on many psychiatric appointments where the psychiatrists had no idea what medications to prescribe.  With my 14 years experience working with people with autism, I have found these health-professionals often ask my opinion on what medication to prescribe.  If only I had known about Melatonin. 

 

Autistic individuals have been shown to have decreased Glutamate transport neurons in the brain.[15]   They also have abnormally high amounts of Glutamate in the blood.[16]  Research shows that there is a direct link between abnormal Glutamate receptors in the brain and the occurrence of autism.[17]

 

Since Melatonin has been shown to be a natural counter-agent to excess Glutamate, it would make Melatonin a logical treatment for Autism.

 

Individuals with autism have also shown a predisposition to sleep-disorders, and could benefit from the sleep inducing effects of Melatonin treatment.

 

Research into the use of Melatonin on people with autism may one day unlock a way to reverse the disorders debilitating effects.

 

 

Stroke and Traumatic Brain Injury

Stacey was a bright young girl.  She had worked hard in high school and graduated with excellent marks.  She wanted to be a teacher and had been accepted into an excellent college for the fall semester.  She never made it there.  Stacey was a passenger in a horrendous car accident.  Her friend behind the wheel died at the scene.  She received a massive blow to her head. 

 

At the hospital the surgeons worked quickly and with considerable expertise.  It was too late.  Blood vessels had broken within her brain, flooding vital areas with chemicals that the sensitive cells within the skull could not cope with.

 

When I first met Stacey she was at a sheltered workshop for the mentally handicapped, putting bolts into plastic bags.  Instead of teaching she was now assisted by trainers, who had to remind her daily which table she sat at and which locker was hers.  Though I saw her almost every day she always greeted me like I was a stranger she had never seen before.  Her dreams of success were shattered by an injury that would shadow her and her family the rest of her life.

 

We are all only one accident away from that future. 

 

Our minds are our most valuable commodity.  The human body is designed to protect us from elements that could cause damage like the kind Stacey experienced.  The blood brain barrier exists to protect the delicate inner workings of the brain from chemicals in the blood that could damage this system.

When Monosodium Glutamate in the blood enters the brain in unregulated amounts neurotoxicity occurs.  Neural cells become over-excited by Glutamate or other excitotoxins and stimulate themselves to death.  Research shows that both hemorrhagic stroke and accidental brain injury can allow this kind of brain damage to occur.

 

In the case of ischemic stroke, the blood supply to an area of the brain is cut off.  Oxygen that regulates crucial chemical levels around the brain cells is in short supply.  Harmful chemicals like nitric oxide and Glutamate can increase to dangerous levels.  These chemicals are considered free radicals, and bond to nerve receptors and other molecules in the brain to cause irreparable damage.

 

In cases of traumatic brain injury, ischemic and hemorrhagic stroke, Melatonin can be highly effective at reducing the damage caused.[18]

 

The anti-oxidizing properties of Melatonin directly reduce the ability of free radicals to collect and harm the vulnerable structures in the brain.  Melatonin injections given within two hours of a stroke dramatically decrease the permanent brain damage that the stroke would have caused.[19] 

 

Melatonin is an effective protective agent, guarding the brain from damage caused by toxic levels of Glutamate in the brain.  In a recent study it was discovered that Melatonin injected into the cerebellum of subjects created a protective effect against Glutamate injected into the same area, while Glutamate injected into the brain of untreated subjects caused neural cell death.[20]  

 

Melatonin, used in the pretreatment of stroke victims, has been shown to reduce the severity of damage in successive strokes by as much as 46%.  Motor, sensory memory, and psychological problems due to stroke could be reduced by treatment with Melatonin.[21] 

 

Since Melatonin has been shown to be beneficial in reducing the severity of brain damage in both stroke and traumatic brain accident victims, perhaps it will become an early response treatment method used by emergency workers and first response teams everywhere. Melatonin has been proven to reduce the amount of permanent debilitating damage from a stroke or brain accident, wouldn’t you be asking for it?

 

Research in this direction raises another question: if toxic levels of Glutamate entering the brain from broken blood vessels can cause increased brain damage in stroke and accident victims, would reducing the amount of Glutamate in your blood also reduce the level of damage that the victim suffers?  Could current stroke or brain accident victims suffer less paralysis and brain damage if they had avoided MSG-laden food in the meal eaten just before their affliction struck them? More studies answering this question are definitely needed. I don’t know about you, but until there is hard evidence to disprove my concern, I’m not taking any chances.

 

I see Stacey now and then, and she still doesn’t remember who I am.

 

 

Epilepsy

 

Melatonin has been proven to defend the brain against attacks by excitotoxic chemicals.[22] MSG can cause epileptic convulsions.  Because Melatonin directly counteracts the free radicals that could be the cause of the brain misfiring to induce epilepsy, it is possible that Melatonin could replace some of the current anti-convulsant medications on the market.  Recent research has even gone as far as to compare the ability of Phenytoin (a commonly prescribed anti-convulsant drug sold under the brand name Dilantin) and Melatonin in reducing epileptic seizures.  The findings of the research “showed a superior protective effect of Melatonin over Phenytoin.”[23]

 

So why wouldn’t Melatonin be prescribed for epilepsy instead of Dilantin?

 

Is Melatonin more dangerous to take than Phenytoin (Dilantin)?  According to www.Rxlist.com, a website that lists drugs and their side effects and is sponsored by major pharmaceutical companies, Melatonin has the side effects of drowsiness, headache, or upset stomach.  Rxlist reports that Dilantin has the following side effects:

Nystagmus, ataxia, slurred speech, decreased coordination and mental confusion. Dizziness, insomnia, transient nervousness, motor twitchings and headache have also been observed as well as  nausea, tardive dyskenesia, constipation, toxic hepatitis and liver damage.  Skin rashes of various sorts including the possibly fatal forms of bullous, exfoliative or purpuric dermatitis, lupus erythematosus, Stevens-Johnson syndrome and toxic epidermal necrolysis.  Also included is thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis and pancytopenia with or without bone marrow suppression, Macrocytosis and megaloblastic anemia, Lymphadenopathy including benign lymph node hyperplasia, pseudolymphoma, lymphoma. Hodgkin's disease has also been reported.  Add to these the side effects of coarsening of the facial features, enlargement of the lips, gingival hyperplasia, hypertrichosis and Peyronie's disease.  Hypersensitivity syndrome (which may include, but is not limited to, symptoms such as arthralgias, eosinophilia, fever, liver dysfunction, lymphadenopathy or rash), systemic lupus erythematosus and immunoglobulin abnormalities.

‘www.rxlist.com’ goes on to report that pregnant women are at risk of having infants with a higher incidence of birth defects, including prenatal growth deficiency, microcephaly and mental deficiency. 

Rxlist reports that overdosing on Melatonin can cause headache, drowsiness and upset stomach. An overdose of 2 to 5 grams of Dilantin is fatal.

So why would Melatonin be overlooked at the doctor’s office, while prescriptions for Dilantin, even with all its side effects, are plentiful?

Money, money, money.

Melatonin is not a patented substance.  It is inexpensive and no pharmaceutical company can monopolize it.  No Melatonin salesmen visit the physician’s office.  No drug company will fund research of it or sing its praises to the FDA or other medical communities.  Why would the drug companies support a plentiful and inexpensive cure, when they can profit from a patent they own?

 

Medication Side Effects

 

Not only can Melatonin replace some anti-seizure and anti- psychotic medications, it can also help against the side effects of them as well. 

 

Tardive Dyskinesia is a prevalent side effect of many anti-seizure medications.  Its symptoms include hand trembling and involuntary facial tics.  Melatonin has been shown to both prevent and reduce Tardive Dyskinesia in test subjects.[24]  People given Melatonin showed a remarkable decrease in the involuntary movements caused by Tardive Dyskinesia.[25]

 

Melatonin can even prevent the serious side effects caused by anti-cancer medications and the radiation therapy provided to cancer patients. 

 

Doxorubicin is a commonly used anti-cancer drug whose side effects include “toxic effects on the cardiovascular system.”[26]  By treating subjects with Melatonin, researches found that Melatonin protected the cardiac system from the harmful side effects of Doxorubicin.[27]

 

Research has also discovered that healthy cells of subjects given whole body irradiation therapy were protected by Melatonin administered before the radiation.[28]

 

Since Melatonin can provide protection from medication and treatment side effects, shouldn’t physicians be offering this information to patients who could benefit from it?

 

 

Alzheimer’s

 

ADHD and autism are not the only neurodegenerative diseases that Melatonin can be helpful in treating.  Both Alzheimer’s and Parkinson’s have been shown to be caused by free radicals like MSG.  Melatonin’s anti-oxidizing properties combat these free radicals, and in doing so could protect against the development of Alzheimer’s.[29]  

 

Elderly people who have chronically low blood sugar are candidates for the development of Alzheimer’s.  Perhaps by using Melatonin as a preventative treatment for this population, the occurrence of this degenerative disease could be substantially reduced.

 

In those patients who already have Alzheimer’s, removal of free Glutamates such as MSG from their diet, along with the addition of Melatonin, could reduce the debilitating effects of the disorder.

 

Both Parkinson’s and Huntington’s disease can be linked to excess Glutamate levels in the brain.  Since Melatonin has been shown to negate the excitotoxic effects of Glutamate,[30] its use as a treatment for people suffering these diseases should be more thoroughly studied.

Schizophrenia

Schizophrenia has been linked to abnormal Glutamate processes in the brain.  With the reduced capacity of the schizophrenic mind to handle increased Glutamate in the brain, the Glutamate itself could cause the symptoms seen in the delusional episodes representative of the disorder.

 

In excess forms, Glutamate acts as a free radical and an excitotoxin.  Melatonin is one of the most effective neutralizers of free radicals in the body.  Melatonin has neuro- protective effects against Monosodium Glutamate’s excitotoxic effects in the brain.[31]

 

Melatonin could act to neutralize the excess Glutamate in patients with schizophrenia, possibly reducing the episodes that disable them.

 

Research that tests the effectiveness of Melatonin on people with schizophrenia could lead to a new way to reduce the debilitating effects of this disorder.

 

Cholesterol, High Blood Pressure and Heart Disease

 

High cholesterol levels and high blood pressure are both indicators of an increased chance of cardiac arrest.  Billions of dollars worth of medications are purchased each year to reduce both cholesterol and the blood pressure of people suffering from these conditions.

 

Melatonin has the amazing ability to solve both these problems at a substantial monetary savings to the medical system and insurance companies.  Melatonin can reduce blood cholesterol levels by as much as 38 percent.  This amount is substantial considering a 10-15 percent cholesterol reduction can result in a 20 to 30 percent reduction in heart attack risk.[32]  

 

Melatonin’s beneficial effects don’t stop there.  90 minutes after taking Melatonin, the blood pressure of people with hypertension returns to normal levels.[33]

 

Research has even shown that Melatonin can reduce the tissue damage done after cardiac arrest, and may even be able to reverse it.[34]

           

How many people suffering from high blood pressure, high cholesterol and even cardiac arrest could be helped if their physicians put down their prescription pads and suggested that their patients add Melatonin to their nightly vitamin intake?

 

 

 

 

 

 

Fluoride Poisoning

Fluoride poisoning by industrial toxic waste is increasing on a global scale.[35]

 

As the union of the workers at the EPA headquarters stated, fluoride causes bone degeneration, neurotoxic effects in the brain, cancer and organ damage.  Many of these disorders have been shown to be reversed by the anti-oxidizing effect of Melatonin. 

 

The ability of the body to protect bone from degeneration can be augmented by increasing Melatonin.[36]  This effect could be helpful against fluoride’s effect of reducing bone strength and causing bone cancers.   

 

Melatonin has a protective effect against loss of bone mass.[37]  It actually increases bone mass and density, promoting greater bone strength.[38]  The ability of Melatonin to act as a scavenger of bone debilitating free radicals can also add to its bone protective properties.[39] 

 

By drinking water that has had the fluoride removed, degenerative skeletal fluorosis can be reversed.[40] 

 

We have already seen the ability of Melatonin to fight toxic levels of poisons in the blood of infants; perhaps it may assist against the fluoride collecting in us as well.  Melatonin could also protect the brain against the fluoride that the EPA employees have stated reduces the IQ levels of children.

 

The visual evidence of Melatonin’s effects are much more compelling proof of its ability to counteract fluoride poisoning.  Scientific research has proven that fluorosis, (the early warning sign that your child has been poisoned by fluoride) is not as irreversible as dentists lead you to believe.[41]

 

Instead of the expensive cosmetic treatments that dentists suggest, fluorosis can be reversed by a diet rich in vitamins and anti-oxidants.[42]  As studies in hundreds of publications have shown, Melatonin is one of the most effective anti-oxidants available.[43]

 

Providing you immediately remove all sources of fluoride in your child’s diet, and catch the poisoning in its early stages, it is possible to reverse the effects of the fluoride poisoning.  Jessi’s teeth once mottled and deformed by fluoride, have shown a remarkable improvement over the past year.  By removing fluoride from our drinking water and adding Melatonin to our nightly routine, we have reversed the fluorosis that inspired this book.

 

Jessi’s smile is prettier than ever.

 

It’s not too late for your children.[44]  Your swift actions can see to that.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



[1] Espinar, A. Garcia-Oliva, A. Isorna, EM. Quesada, A. Prada, FA. Guerrero, JM. “Neuroprotection by melatonin from Glutamate-induced excitotoxicity during development of the cerebellum in the chick embryo.”  J Pineal Res 2000 Mar;28(2):81-8.

 

[2] Tan, DX. Reiter, RJ. Manchester, LC. Yan, MT. El-Sawi, M. Sainz, RM. Mayo, JC. Kohen, R. Allegra, M. Hardeland, R. “Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.”  Curr Top Med Chem 2002 Feb;2(2):181-97.

 

[3] Jan, JE. O'Donnell, ME.  “Use of melatonin in the treatment of paediatric sleep disorders.”   J Pineal Res 1996 Nov;21(4):193-9.

 

[4] Smits, MG. Nagtegaal, EE. Van der Heijden, J. Coenen, AM. Kerkhof, GA.  “Melatonin for chronic sleep onset insomnia in children: a randomized placebo-controlled trial.”  J Child Neurol 2001 Feb;16(2):86-92.

 

[5] Johnson, K. Page, A. Williams, H. Wassemer, E. Whitehouse, W.  “The use of melatonin as an alternative to sedation in uncooperative children undergoing an MRI examination.”  Clin Radiol 2002 Jun;57(6):502-6.

 

[6] Jan JE, O'Donnell ME.  “Use of melatonin in the treatment of pediatric sleep disorders.” J Pineal Res 1996Nov;21(4):193-9.

 

[7] Singh, P. Bhargava, VK. Garg, SK.   “Effect of melatonin and beta-carotene on indomethacin induced gastric mucosal injury.”  Indian J Physiol Pharmacol 2002 Apr;46(2):229-34.

 

[8] Bubenik GA.  “Gastrointestinal melatonin: localization, function, and clinical relevance.” Dig Dis Sci 2002 Oct;47(10):2336-48.

 

 

[9] Cardinali, DP. Ladizesky, MG. Boggio, V. Cutrera, RA. Mautalen, C.  “Melatonin effects on bone: experimental facts and clinical perspectives.”   J Pineal Res 2003 Mar;34(2):81-7.

 

[10] Arnold, LE. Pinkham, SM. Votolato, N.  Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder?”  J Child Adolesc Psychopharmacol 2000 SUMMMER;10(2):111-7.  

 

[11] Zisapel, N.  “Melatonin-dopamine interactions: from basic neurochemistry to a clinical setting.”  Cell Mol Neurobiol 2001 Dec;21(6):605-16.

 

[12] RXLIST, Clinical Pharmacology. http://www.rxlist.com/cgi/generic/methphen_cp.htm.

[13] Appenrodt, E. Schwarzberg, H.  ‘Methylphenidate-induced motor activity in rats: modulation by melatonin and vasopressin.’  Pharmacol Biochem Behav 2003 Apr;75(1):67-73.

 

[14] Kulman, G. Lissoni, P. Rovelli, F.  Roselli, MG. Brivio, F. Sequeri, P.  “Evidence of pineal endocrine hypofunction in autistic children.”   Neuroendocrinol Lett 2000;21(1):31-34.

 

[15] Purcell, AE. Jeon, OH. Zimmerman, AW. Blue, ME. Pevsner, J.  “Postmortem brain abnormalities of the Glutamate neurotransmitter system in autism.”  Neurology 2001 Nov 13;57(9):1618-28.

 

[16] Fatemi, SH. Halt, AR. Stary, JM. Kanodia, R. Schulz, SC. Realmuto, GR.  “Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices.”  Biol Psychiatry 2002 Oct 15;52(8):805-10.

 

[17] Jamain, S. Betancur, C. Quach, H. Philippe, A. Fellous, M. Giros, B. Gillberg, C. Leboyer, M. Bourgeron, T. “Linkage and association of the Glutamate receptor 6 gene with autism.”  Mol Psychiatry 2002;7(3):302-10.

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